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Products > Neuro Signaling > Gama Secretase > YO 01027 (Dibenzazepine, DBZ)
Product name : YO 01027 (Dibenzazepine, DBZ)
Item : cc425
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 209984-56-5
Molecular Weight : 463.48
Formula : C₂₆H₂₃F₂N₃O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
YO-01027 (Dibenzazepine, DBZ) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 and 2.9 nM for the proteolysis of amyloid precursor protein-like (APPL) and Notch, respectively.  [1][2]
 
Reference:
[1] Mol. Pharmacol. 2010, 77, 567-574.
[2] Cancer Res. 2010, 70, 709-718.
 
 
Chemical Information
Molecular Weight (WM):
463.48
Formula:
C26H23F2N3O3
CAS No:
209984-56-5
Purity:
≥ 98%
Synonyms:
YO01027
 
DMSO ≥ 93mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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