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Product name : Abiraterone (CB 7598)
Item : cc239
Price : 10mg, $225; 50mg, $695; 100mg, $1195; 200mg, $1895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Abiraterone (CB-7598) is a potent CYP17 inhibitor with IC50 of 2 nM. Abiraterone (CB7598) inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.  [1][2]
 
Reference:
[1] J Clin. Oncol. 2008, 26, 4563-4571.
[2] J Med. Chem. 2010, 53, 5749-5758.
 
 
Chemical Information
Molecular Weight (WM):
349.51
Formula:
C24H31NO
CAS No:
154229-19-3
Purity:
≥ 98%
Synonyms:
 
 
DMSO < 1 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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