XL647/XL-647/XL 647/EXEL7647/EXEL-7647/EXEL 7647/651031-01-5/874286-84-7/781613-23-8/1000599-06-3/acesobio supply

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Products > Receptor Tyrosine Kinase > EGFR > XL 647 (EXEL 7647)

Product name : XL 647 (EXEL 7647)

Item : cc224

Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190

contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.

CAS : 781613-23-8

Molecular Weight : 491.39

Formula : C₂₄H₂₅Cl₂FN₄O₂

Storage : at -20°C

Additional information : We offer significant discount for bulky quantity order

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Details:

XL647 (EXEL-7647) is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including EGFR, HER2, ERBB2, VEGFR and EphB4. ^[1][2]

Reference:

[1] Clin. Cancer Res. 2008, 14, 2465-2475.

[2] Clin. Cancer Res. 2007, 13, 3713-3723.

Chemical Information

Molecular Weight (WM):	491.39
Formula:	C₂₄H₂₅Cl₂FN₄O₂
CAS No:	651031-01-5, 874286-84-7, 781613-23-8, 1000599-06-3 ( 4-methylbenzenesulfonate)
Purity:	≥ 98%
Synonyms:	EXEL7647, XL-647
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	2 months -80℃ in DMSO