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Product name : XL 647 (EXEL 7647)
Item : cc224
Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 781613-23-8
Molecular Weight : 491.39
Formula : C₂₄H₂₅Cl₂FN₄O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
XL647 (EXEL-7647) is an orally bioavailable small-molecule RTK inhibitor that binds to and inhibits several tyrosine receptor kinases that play major roles in tumor cell proliferation and tumor vascularization, including EGFR, HER2, ERBB2, VEGFR and EphB4.  [1][2]
 
Reference:
[1] Clin. Cancer Res. 2008, 14, 2465-2475.
[2] Clin. Cancer Res. 2007, 13, 3713-3723.
 
  
Chemical Information
Molecular Weight (WM):
491.39
Formula:
C24H25Cl2FN4O2
CAS No:
651031-01-5, 874286-84-7, 781613-23-8, 1000599-06-3 ( 4-methylbenzenesulfonate)
Purity:
≥ 98%
Synonyms:
EXEL7647, XL-647
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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