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Products > PI3K/Akt/mTOR > GSK-3 > SB 415286
Product name : SB 415286
Item : cc259
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 264218-23-7
Molecular Weight : 359.72
Formula : C₁₆H₁₀ClN₃O₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
SB415286 is a potent GSK3α and GSK3β inhibitor with IC50 of 78 nM and ~78 nM, respectively. SB-415286 has minimal activity against 24 other protein kinases (IC50 > 10 μ M). SB 415286 stimulates glycogen synthesis, gene transcription and is neuroprotective.  [1][2]
 
Reference:
[1] J Neurochem. 2001, 77, 94-102.
[2] Cancer Res. 2005, 65, 1961-1972.
 
 
Chemical Information
Molecular Weight (WM):
359.72
Formula:
C16H10ClN3O5
CAS No:
264218-23-7
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 72 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 72 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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