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Product name : Apatinib (YN968D1)
Item : cc605
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1218779-75-9
Molecular Weight : 493.58
Formula : C₂₅H₂₇N₅O₄S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Apatinib (YN968D1) is a small-molecule selective multitargeted tyrosine kinase inhibitor with an IC50 of 2.43 nM for the inhibition of VEGFR2. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases.   [1][2]
 
Reference:
[1] BMC Cancer 2010, 10, 529.
[2] Cancer Res. 2010, 70, 7981-7991.
 
 
Chemical Information
Molecular Weight (WM):
493.58
Formula:
C25H27N5O4S
CAS No:
811803-05-1
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 99 mg/mL
Solubility (25℃)
Water ≥ 8 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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