Apoptosis
Telomerase
|
Product name : CH 5132799
Item : cc614
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1007207-67-1
Molecular Weight : 377.42
Formula : C₁₅H₁₉N₇O₃S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 |
| Details: | ||||||||||||||||||||
CH5132799, a novel class I PI3K inhibitor, exhibits a strong inhibitory activity especially against PI3Kα with IC50 with 0.014 μM. CH-5132799 selectively inhibits class I PI3Ks, PI3Kα (IC50 = 0.014 μM ), PI3Kβ (IC50 = 0.12 μM ), PI3Kδ (IC50 = 0.50 μM ), PI3Kγ (IC50 = 0.036 μM ), but shows less inhibition of class II PI3Ks, class III PI3k and mTOR and also no inhibitory activity (IC50 > 10 μM) against 26 protein kinases. [1][2]
Reference:
[1] Clin.Cancer Res. 2011, 17, 3272-3281.
[2] Bioorg. Med. Chem. Lett. 2011, 21, 1767-1772.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian