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Product name : CH 5132799
Item : cc614
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1007207-67-1
Molecular Weight : 377.42
Formula : C₁₅H₁₉N₇O₃S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
CH5132799, a novel class I PI3K inhibitor, exhibits a strong inhibitory activity especially against PI3Kα with IC50 with 0.014 μM. CH-5132799 selectively inhibits class I PI3Ks, PI3Kα (IC50 = 0.014 μM ), PI3Kβ (IC50 = 0.12 μM ), PI3Kδ (IC50 = 0.50 μM ), PI3Kγ (IC50 = 0.036 μM ), but shows less inhibition of class II PI3Ks, class III PI3k and mTOR and also no inhibitory activity (IC50 > 10 μM) against 26 protein kinases.  [1][2]
 
Reference:
[1] Clin.Cancer Res. 2011, 17, 3272-3281.
[2] Bioorg. Med. Chem. Lett. 2011, 21, 1767-1772.
 
 
Chemical Information
Molecular Weight (WM):
377.42
Formula:
C15H19N7O3S
CAS No:
1007207-67-1
Purity:
≥ 98%
Synonyms:
CH 5132799
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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