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Product name : Triciribine
Item : cc615
Price : 10mg, $195; 50mg, $595; 100mg, $995; 200mg, $1455
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Triciribine (TCN, API-2) is a DNA synthesis inhibitor and also inhibits Akt phosphorylation and HIV-1 with IC50 with 130 nM and 20 nM, respectively. Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery, including Bcl-xL/Bcl-2-associated death promoter (BAD) and caspase 9.   [1][2]
 
Reference:
[1] Clin. Cancer Res. 2007, 13, 5883-5888.
[2] Cancer Res. 2004, 64, 4394-4399.
 
 
Chemical Information
Molecular Weight (WM):
320.30
Formula:
C13H16N6O4
CAS No:
35943-35-2
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 64 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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