Favorite  |  Set Home
Products > PI3K/Akt/mTOR > Akt > Triciribine
Product name : Triciribine
Item : cc615
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 35943-35-2
Molecular Weight : 320.3
Formula : C₁₃H₁₆N₆O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Triciribine (TCN, API-2) is a DNA synthesis inhibitor and also inhibits Akt phosphorylation and HIV-1 with IC50 with 130 nM and 20 nM, respectively. Triciribine inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3, which may result in the inhibition of Akt-expressing tumor cell proliferation. Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery, including Bcl-xL/Bcl-2-associated death promoter (BAD) and caspase 9.   [1][2]
 
Reference:
[1] Clin. Cancer Res. 2007, 13, 5883-5888.
[2] Cancer Res. 2004, 64, 4394-4399.
 
 
Chemical Information
Molecular Weight (WM):
320.30
Formula:
C13H16N6O4
CAS No:
35943-35-2
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 64 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
AKT inhibitor VIII
AKT inhibitor VIII
Price: 200mg, $659;500mg, $1150; 1g, $1595; 2g, $2355
A 674563
A 674563
Price: 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
PHT 427
PHT 427
Price: 200mg, $649;500mg, $1050; 1g $1595; 2g, $2355
GSK 690693
GSK 690693
Price: 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
MK 2206
MK 2206
Price: 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
Akt Inhibitor IV
Akt Inhibitor IV
Price: 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
AZD 5363
AZD 5363
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
BX 795
BX 795
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590