Product name : MK 5108 (VX 689)
Item : cc619
Price : 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1010085-13-8
Molecular Weight : 461.94
Formula : C₂₂H₂₁ClFN₃O₃S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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MK-5108 (VX-689) is a highly selective Aurora-A kinase inhibitor with an IC50 of 0.064 nM. MK5108 (VX689) inhibited growth of human tumor cell lines in culture and in different xenograft models. Furthermore, the combination of MK 5108 and docetaxel showed enhanced antitumor activities compared with control and docetaxel alone-treated animals without exacerbating the adverse effects of docetaxel. [1][2]
Reference:
[1] Mol. Cancer Ther. 2010, 9, 157-166.
[2] Clin. Cancer Res. 2012, 18, 3352-3365.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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