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Product name : MK 3207
Item : cc623
Price : 10mg, $225; 50mg, $695; 100mg, $1195; 200mg, $1795
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
MK-3207 is a calcitonin gene-related peptide (CGRP) receptor antagonist with IC50 of 0.12 nM. MK3207 displays marked selectivity for human CGRP receptor versus related human AM1 (CLR/RAMP2) receptor, AM2 (CLR/RAMP3) receptor, AMY3 (CTR/RAMP3) receptor, and CTR with Ki values of 16.5 μM, 0.156 μM, 0.128 μM and 1.9 μM, respectively.   [1][2]
 
Reference:
[1] J Pharmacol. Exp. Ther. 2010, 333, 152-160.
[2] ACS Med. Chem. Lett. 2010, 1, 24-29.
 
 
Chemical Information
Molecular Weight (WM):
594.05
Formula:
C31H29F2N5O3.HCl
CAS No:
957116-20-0, 957118-49-9 (free base)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 119 mg/mL
Solubility (25℃)
Water ≥ 5 mg/mL
 
Ethanol ≥ 119 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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