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Products > GPCR > Endothelin Receptor > Zibotentan (ZD 4054)
Product name : Zibotentan (ZD 4054)
Item : cc635
Price : 10mg, $225; 50mg, $695; 100mg, $1195; 200mg, $1895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Zibotentan (ZD4054) is a specific Endothelin A receptor (ETA) antagonist with IC50 of 21 nM. Zibotentan (ZD-4054) binds selectively to the ET-A receptor, thereby inhibiting endothelin-mediated mechanisms that promote tumor cell proliferation. [1][2]
 
Reference:
[1] J Med. Chem. 2007, 50, 6-9.
[2] Biochem. J 2009, 424, 47-60.

 
Chemical Information
Molecular Weight (WM):
424.43
Formula:
C19H16N6O4S
CAS No:
186497-07-4
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 14 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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