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Product name : CX 4945 (silmitasertib)
Item : cc639
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1009820-21-6
Molecular Weight : 349.77
Formula : C₁₉H₁₂ClN₃O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
CX 4945 (Silmitasertib) is an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CX-4945 selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival. [1][2]
 
 
Reference:
[1] Cancer Res. 2010, 70, 10288-10298.
[2] Mol. Cell Biochem. 2011, 356, 37-43.
 
 
 
Chemical Information
Molecular Weight (WM):
349.77
Formula:
C19H12ClN3O2
CAS No:
1009820-21-6, 1309357-15-0 (sodium salt)
Purity:
≥ 98%
Synonyms:
CX4945
 
DMSO ≥ 16 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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