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Product name : WZ 811
Item : cc645
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 55778-02-4
Molecular Weight : 290.36
Formula : C₁₈H₁₈N₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
WZ811 is a C-X-C chemokine receptor type 4 (CXCR4) antagonist. WZ-811 shows subnanomolar potency (EC50 = 0.3 nM) in an affinity binding assay. The CXC chemokine receptor-4 (CXCR4) is a G protein-coupled receptor that is specific for stromal cell-derived factor-1 (SDF-1, CXCL12). Activation of CXCR4 promotes homing of hematopoietic stem cells, chemotaxis and quiescence of lymphocytes, and growth and metastasis of certain cancer cell types. [1][2]
 
Reference:
[1] J Med. Chem. 2007, 50, 5655-5664.
[2] J Med. Chem. 2010, 53, 8556-8568.
 
 
Chemical Information
Molecular Weight (WM):
290.36
Formula:
C18H18N4
CAS No:
55778-02-4
Purity:
≥ 98%
Synonyms:
WZ 811
 
DMSO ≥ 30 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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