Apoptosis
Serotonin Transporter
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Product name : SB 742457 (GSK 742457)
Item : cc 657
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 607742-69-8
Molecular Weight : 353.44
Formula : C₁₉H₁₉N₃O₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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SB-742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63. SB-742457 extends into Alzheimer disease (AD) sufferers further highlights the therapeutic promise of this mechanistic approach. It is increasingly clear that blockade of 5-HT6 receptors leads to an improvement of cognitive performance in a wide variety of learning and memory paradigms and also results in anxiolytic and antidepressant-like activity. SB742457 is generally safe and well tolerated and may be efficacious in Alzheimer disease. [1][2]
Reference:
[1] Curr. Alzheimer Res. 2010, 7, 374-385.
[2] Curr. Opin. Pharmacol. 2011, 11, 94-100.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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