Product name : AMG 900
Item : cc-2
Price : 200mg, $1750;500mg, $2350; 1g $2950; 2g, $4150
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 945595-80-2
Molecular Weight : 503.58
Formula : C₂₈H₂₁N₇OS
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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AMG 900 is a small-molecule inhibitor of Pan-aurora kinases with an IC50 of median 3.5 nM. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities of Aurora kinases A, B and C, which may result in inhibition of cellular division and proliferation in tumor cells that overexpress these kinases. Aurora kinases are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis and are overexpressed by a wide variety of cancer cell types.[1][2]
Reference:
[1] Caner Res. 2010, 70, 9846-9854.
[2] Xenobiotica 2010, 41, 400-408.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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