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Product name : Daunorubicin (Daunomycin)
Item : cc 663
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 23541-50-6
Molecular Weight : 563.98
Formula : C₂₇H₃₀ClNO₁₀
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Daunorubicin HCl (Daunomycin) inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM. Daunorubicin is a DNA intercalating anthracylcine natural product isolated from Streptomyces peucetius. Upon intercalation, Daunorubicin forms stable complexes with the DNA backbone, inhibiting normal functioning of the double helix and the proteins that interact with it. The action of Daunorubicin has been correlated to efficacy in suppressing the proliferation of certain acute leukemias. [1][2]
 
Reference:
[1] J Med. Chem. 1996, 39, 4135-4138.
[2] JJ Biomol. Struct. 2004, 21, 713-724.
 
 
Chemical Information
Molecular Weight (WM):
563.98
Formula:
C27H29NO10.HCl
CAS No:
23541-50-6, 20830-81-3 (free base)
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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