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Product name : NSC 23766
Item : cc 673
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 733767-34-5
Molecular Weight : 421.58
Formula : C₂₄H₃₅N₇
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
NSC 23766 is a specific inhibitor of the binding and activation of RAC GTPase.NSC-23766Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TpioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation. NSC23766 inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells.   [1][2]
 
Reference:
[1] Proc. Natl. Acad. Sci. USA 2004, 101, 7618-7623.
[2] Clin. Exp. Metastasis. 2010, 27, 481-491.
 
 
Chemical Information
Molecular Weight (WM):
458.04
Formula:
C24H36ClN7
CAS No:
733767-34-5   
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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