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Product name : BYL 719
Item : cc 697
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1217486-61-7
Molecular Weight : 441.47
Formula : C₁₉H₂₂F₃N₅O₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
BYL-719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.  [1]
 
Reference:
[1] Dejan Juric, et al. 2012, AACR 103rd Annual Meeting. Abst CT-01
 
 
Chemical Information
Molecular Weight (WM):
441.47
Formula:
C19H22F3N5O2S
CAS No:
1217486-61-7
Purity:
≥ 98%
Synonyms:
BYL 719
 
DMSO ≥ 88 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 5 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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