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Product name : ZM323881 hydrochloride
Item : cc 699
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 193000-39-4
Molecular Weight : 411.86
Formula : C₂₂H₁₉ClFN₃O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
ZM-323881 is a potent and selective inhibitor of VEGF-R2 tyrosine kinase in vitro (IC(50) < 2 nM), compared with other receptor tyrosine kinases, including VEGF-R1 (IC(50) > 50 microM). ZM323881 inhibits VEGF-A-induced endothelial cell proliferation (IC(50) = 8 nM) and VEGF-R2 tyrosine phosphorylation in vitro.   [1][2]
 
Reference:
[1] J Recept. Signal Transduct. Res. 2003, 23, 239-254.
[2] J Clin. Endocrinol. Metab. 2006, 91, 4603-4611.
                                                                              
 
Chemical Information
Molecular Weight (WM):
411.86
Formula:
C22H18FN3O2.HCl
CAS No:
324077-30-7
Purity:
≥ 98%
Synonyms:
ZM 323881
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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