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Products > DNA damage > HDAC > Tacedinaline (CI 994, PD 123654)
Product name : Tacedinaline (CI 994, PD 123654)
Item : cc 701
Price : 50mg, $195; 100mg, $395; 200mg, $695, 1g, $1295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 μM. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations.  [1][2]
 
Reference:
[1] Bioorg. Med. Chem. Lett. 2008, 18, 973-978.
[2] Oncol. Rep. 2008, 19, 1517-1523.
                                                                              
 
Chemical Information
Molecular Weight (WM):
269.30
Formula:
C15H15N3O2
CAS No:
112522-64-2, 1299346-14-7 (HCl), 1353653-79-8 (TFA)
Purity:
≥ 98%
Synonyms:
PD-123654, PD123654, CI-994
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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