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Product name : XMD 8-92
Item : cc733
Price : 200mg, $795; 500mg, $1495
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
Additional Information : We offer significant discount for bulky quantity order
CAS : 1234480-50-2
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Details:
XMD 8-92 is shown to be an extremely selective ERK5/BMK1 inhibitor (KD values are 80, 190, 600 and 890 nM for BMK1, DCAMKL2, PLK4 and TNK1 respectively). that presents selectivity over 402 diverse kinases. This compound is shown to be an anti-proliferative agent via inhibition of growth factor-induced activation of cellular BMK1 and reducing of BMK1 activity in in vitro kinase assays.  [1][2]
 
Reference:
[1] Cancer Cell 2010, 18, 258-267.
[2] ACS Med. Chem. Lett. 2011, 2, 195-200.
                                          
Chemical Information
Molecular Weight (WM):
474.55
Formula:
C26H30N6O3
CAS No:
1234480-50-2
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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