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Product name : SCH 1473759
Item : cc759
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
CAS : 1094069-99-4
Molecular Weight : 426.54
Formula : C₂₀H₂₆N₈OS
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
SCH-1473759 is a novel sub-nanomolar Aurora A/B inhibitor. SCH1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH-1473759 demonstrated potent mechanism-based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. [1][2]
 
Reference:
[1] ACS Med. Chem. Lett. 2010, 5, 214-218.
[2] Chemother. Pharmacol. 2011, 68, 923-933.
Chemical Information
Molecular Weight (WM):
426.54
Formula:
C20H26N8OS
CAS No:
1094069-99-4, 1094067-13-6 (HCl)
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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