Favorite  |  Set Home
Products > Aurora/Ksp > Aurora > SCH 1473759
Product name : SCH 1473759
Item : cc759
Price : 10mg, $375; 50mg, $895; 100mg, $1295;200mg, $1995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
             [Next Product]→


Details:
SCH-1473759 is a novel sub-nanomolar Aurora A/B inhibitor. SCH1473759 was active against a large panel of tumor cell lines from different tissue origin and genetic backgrounds. SCH-1473759 demonstrated potent mechanism-based activity, and activity was shown to be enhanced in combination with taxanes and KSP inhibitors. This information may be useful for optimizing the clinical efficacy of Aurora inhibitors. [1][2]
 
Reference:
[1] ACS Med. Chem. Lett. 2010, 5, 214-218.
[2] Chemother. Pharmacol. 2011, 68, 923-933.
Chemical Information
Molecular Weight (WM):
426.54
Formula:
C20H26N8OS
CAS No:
1094069-99-4, 1094067-13-6 (HCl)
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
MLN 8054
MLN 8054
Price: 10mg, $275; 50mg, $845; 100mg, $1295; 200mg, $2295
ENMD 2076
ENMD 2076
Price: 200mg, $945; 500mg, $1785
PHA 680632
PHA 680632
Price: 10mg, $275; 50mg, $895; 100mg, $1295; 200mg, $2095
CCT 129202
CCT 129202
Price: 10mg, $225; 50mg, $775; 100mg, $1275; 200mg, $1975
CCT 137690
CCT 137690
Price: 10mg, $125; 50mg, $495; 100mg, $895; 200mg, $1495
VX 680
VX 680
Price: 25mg, $39; 50mg, $75; 100mg, $125; 250mg, $1950
AT 9283
AT 9283
Price: 10mg, $225; 50mg, $755; 100mg, $1175; 200mg, $1675
PF 03814735
PF 03814735
Price: 10mg, $275; 50mg, $695; 100mg, $1295; 200mg, $2295