Apoptosis
Telomerase
|
Product name : PIK 75
Item : cc766
Price : 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
CAS : 372196-77-5
Molecular Weight : 488.74
Formula : C₁₆H₁₅BrClN₅O₄S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
 |
| Details: | |||||||||||||||||||
PIK-75 blocks production of PIP2 and/or PIP3, phosphorylation of Akt, and activation of mTORC1 in adipocytes and myotubes. PI 3-kinase (PI3K) catalyzes the synthesis of the second messengers PtdIns-(3)-P, PtdIns-(3,4)-P2, and PtdIns-(3,4,5)-P3. PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM. PIK-75 inhibits p110γ and p110β considerably less effectively. [1][2]
Reference:
[1] Biochem. Biophys. Res. Commun. 2009, 381, 577-581.
[2] Blood 2007, 110, 4243-4252.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian