Apoptosis
VDAC
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Product name : Tariquidar (XR 9576)
Item : cc775
Price : 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
contact : Send inquiry to: info@acesobio.com
CAS : 206873-63-4
Molecular Weight : 646.73
Formula : C₃₈H₃₈N₄O₆
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Tariquidar (XR-9576) is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer. Tariquidar non-competitively binds to the p-glycoprotein transporter, thereby inhibiting transmembrane transport of anticancer drugs. Inhibition of transmembrane transport may result in increased intracellular concentrations of an anticancer drug, thereby augmenting its cytotoxicity. [1][2]
Reference:
[1] J Med. Chem. 2011, 54, 5878-5889.
[2] J Biol. Chem. 2012, 287, 26806-20816.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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