Product name : PHA 680632
Item : cc-476
Price : 200mg, $1750;500mg, $2350; 1g $2950; 2g, $4150
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 398493-79-3
Molecular Weight : 501.62
Formula : C₂₈H₃₅N₇O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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PHA-680632 is the first representative of a new class of Aurora inhibitors (Aurora A/B/C IC50 at 27, 135 and 120 nM, respectively). This agent has a high potential for further development as an anticancer therapeutic. PHA-680632 is active on a wide range of cancer cell lines and shows significant tumor growth inhibition in different animal tumor models at well-tolerated doses. The IC50 of PHA-680632 for cell anti-proliferation ranged from 0.11 µM to 5.6 µM. [1]
Reference:
[1] Clin. Cancer Res. 2006, 12, 4080-4089.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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