Favorite  |  Set Home
Products > Others > > GSK 126
Product name : GSK 126
Item : cc795
Price : 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
CAS : 1346574-57-9
Molecular Weight : 526.67
Formula : C₃₁H₃₈N₆O₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
GSK-126 is a potent, highly selective, S-adenosyl-methionine-competitive, small-molecule inhibitor of EZH2 methyltransferase activity. GSK126 decreases global H3K27me3 levels and reactivates silenced PRC2 target genes. GSK126 effectively inhibits the proliferation of EZH2 mutant DLBCL cell lines and markedly inhibits the growth of EZH2 mutant DLBCL xenografts in mice. Together, these data demonstrate that pharmacological inhibition of EZH2 activity may provide a promising treatment for EZH2 mutant lymphoma. [1]
 
Reference:
[1] Nature 2012, 492, 108-112.
 
Chemical Information
Molecular Weight (WM):
526.67
Formula:
C31H38N6O2
CAS No:
1346574-57-9
Purity:
≥ 98%
Synonyms:
GSK126
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
HS-173
HS-173
Price: 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
LY 573636 (Tasisulam)
LY 573636 (Tasisulam)
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
Y320
Y320
Price: 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
Tirasemtiv
Tirasemtiv
Price: 200mg, $659;500mg, $1150; 1g, $1595; 2g, $2355
(+) Etomoxir sodium salt
(+) Etomoxir sodium salt
Price: 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
SC 26196
SC 26196
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
N6022
N6022
Price: 200mg, $659;500mg, $1150; 1g, $1595; 2g, $2355
Gadobutrol (Gadavist)
Gadobutrol (Gadavist)
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795