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Products > DNA damage > Topoisomerase > Ixabepilone (BMS -247550)
Product name : Ixabepilone (BMS -247550)
Item : cc806
Price : 10mg, $475; 50mg, $1295; 100mg, $1995;200mg, $3295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Ixabepilone (BMS-247550) is an orally bioavailable semisynthetic analogue of epothilone B with antineoplastic activity. Ixabepilone binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This agent demonstrates antineoplastic activity against taxane-resistant cell lines. [1][2]
 
Reference:
[1] Clin. Cancer Res. 2001, 7, 1429-1437.
[2] Cancer Res. 2002, 62, 466-471.
 
Chemical Information
Molecular Weight (WM):
506.70
Formula:
C27H42N2O5S
CAS No:
219989-84-1
Purity:
≥ 98%
Synonyms:
BMS247550
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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