Idarubicin/Idamycin/Zavedos/58957-92-9/57852-57-0/acesobio supply

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Products > DNA damage > Topoisomerase > Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin)

Product name : Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin)

Item : cc808

Price : 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590

contact : Send inquiry to: info@acesobio.com

CAS : 57852-57-0

Molecular Weight : 533.95

Formula : C₂₆H₂₈ClNO₉

Storage : at -20°C

Additional information : We offer significant discount for bulky quantity order

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Details:

Idarubicin HCl (Idamycin, Zavedos, 4-demethoxydaunorubicin) is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL. Idarubicin intercalates into DNA and interferes with the activity of topoisomerase II, thereby inhibiting DNA replication, RNA transcription and protein synthesis. Due to its high lipophilicity, idarubicin penetrates cell membranes more efficiently than other anthracycline antibiotic compounds.^[1][2]

Reference:

[1] J Chemother. 2005, 17, 663-667.

[2] Hematology. 2004, 9, 217-221.

Chemical Information

Molecular Weight (WM):	497.49
Formula:	C₂₆H₂₇NO₉
CAS No:	58957-92-9, 57852-57-0 (HCl)
Purity:	≥ 98%
Synonyms:
	DMSO ≥ 107 mg/mL
Solubility (25℃)	Water ≥ 10 mg/mL
	Ethanol < 1 mg/mL
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	2 months -80℃ in DMSO