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Product name : CM 346(Afobazol)
Item : CR1873
Price : 100mg, $945; 200mg, $1485
contact : Send inquiry to: info@acesobio.com
Additional Information :  We offer significant discount for bulky quantity order,Please ask price and availability of other quantities
CAS : 173352-21-1
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Details:
 

Chemical Information

M.Wt 307.41 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C15H21N3O2S
CAS No 173352-21-1
Solubility

DMSO



Biological Activity of Afobazole

 

Afobazole (CM346) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.
IC50 value:
Target: anxiolytic agent
Afobazole's mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

 

[1]. Afobazole, From Wikipedia


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