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Product name : XEN445
Item : CR1846
Price : 100mg, $845; 200mg, $1285
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Additional Information :  We offer significant discount for bulky quantity order,Please ask price and availability of other quantities
CAS : 1515856-92-4
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Details:
 Name: XEN445

CAS#:1515856-92-4

Chemical Formula: C18H17F3N2O3
Exact Mass: 366.11913
Molecular Weight: 366.33
Elemental Analysis: C, 59.02; H, 4.68; F, 15.56; N, 7.65; O, 13.10


Description of XEN445: XEN445 is potent and selective endothelial lipase inhibitor, that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice.  Endothelial lipase (EL) activity has been implicated in HDL metabolism and in atherosclerotic plaque development; inhibitors are proposed to be efficacious in the treatment of dyslipidemia related cardiovascular disease.



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