Product name : Lee011
Item : CR1779
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com
CAS : 1256963-02-6
Molecular Weight : 440.97226
Formula : C22H29ClN8
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order,Please ask price and availability of other quantities
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Chemical Information
Biological Activity of CDK4-IN-1
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM; 1500 and 500 fold than CDK1/Cyclin B (IC50>15 uM) and CDK2/Cyclin A (IC50=5.265 uM) respectively.
References on CDK4-IN-1[1]. Cho YS, et al. 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6. J Med Chem. 2010 Nov 25;53(22):7938-57. |
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