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Product name : GSK-2018682
Item : C2471
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $5395
contact : Send inquiry to: info@acesobio.com
CAS : 1034688-30-6
Molecular Weight : 440.884
Formula : C22H21ClN4O4
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
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Details:
Description of:GSK-2018682(CAS:1034688-30-6)
GSK-2018682 is a sphingosine 1 phosphate receptor (S1PR)-1 agonist potentially for the treatment of multiple sclerosis. GSK-2018682 induced acute, transient and non-symptomatic decreases in heart rate and blood pressure.

Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data. 

REFERENCES

1: Subei AM, Cohen JA. Sphingosine 1-phosphate receptor modulators in multiple sclerosis. CNS Drugs. 2015 Jul;29(7):565-75. doi: 10.1007/s40263-015-0261-z. Review. PubMed PMID: 26239599; PubMed Central PMCID: PMC4554772.

2: Xu J, Gray F, Henderson A, Hicks K, Yang J, Thompson P, Oliver J. Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers. Clin Pharmacol Drug Dev. 2014 May;3(3):170-8. doi: 10.1002/cpdd.98. PubMed PMID: 27128606.



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