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Product name : Ticagrelor (AZD 6140)
Item : cc291
Price : 10mg, $195; 50mg, $595; 100mg, $895; 200mg, $1355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Ticagrelor (AR-C 126532XX, AZD-6140) blocks adenosine diphosphate (ADP) receptors of subtype P2Y12. In contrast to the other antiplatelet drugs, ticagrelor has a binding site different from ADP, making it an allosteric antagonist, and the blockage is reversible. Moreover, the drug does not need hepatic activation, which might work better for patients with genetic variants regarding the enzyme CYP2C19 (although it is not certain whether clopidogrel is significantly influenced by such variants). [1][2]
 
Reference:
[1] Bioorg. Med. Chem. Lett. 2007, 17, 6013-6018.
[2] Am. Coll. Cardiol. 2007, 50, 2196.
 
 
Chemical Information
Molecular Weight (WM):
522.57
Formula:
C23H28F2N6O4S
CAS No:
274693-27-5
Purity:
≥ 98%
Synonyms:
AZD6140
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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