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Product name : AMG 073
Item : cc572
Price : 10mg, $95, 50mg, $295; 100mg, $525; 200mg, $925
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. The current study evaluates the efficacy and safety of AMG073 when added to conventional treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD).  [1][2]
 
Reference:
[1] J Am. Soc. Nephrol. 2003, 14, 575-583.
[2] J Clin. Endocrinol. Metab. 2003, 88, 5644-5649.
 
 
Chemical Information
Molecular Weight (WM):
393.87
Formula:
C22H22F3N.HCl
CAS No:
364782-34-3, 226256-56-0 (free base), 1025064-29-2 (acetate)
Purity:
≥ 98%
Synonyms:
Mimpara, Sensipar
 
DMSO ≥ 79 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 33 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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