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Product name : NPS 2143
Item : cc312
Price : 10mg, $75, 50mg, $375; 100mg, $675; 200mg, $995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM in HEK 293 cells. NPS2143 blocks increases in cytoplasmic Ca2+ concentrations with IC50 of 43 nM elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. NPS 2143 stimulates parathyroid hormone (PTH) secretion from bovine parathyroid cells with EC50 of 41 nM.   [1][2]
 
Reference:
[1] J Pharmacol. Exp. Ther. 2001, 299, 323-331.
[2] J Biol. Chem. 2010, 285, 1016-1022.
 
 
Chemical Information
Molecular Weight (WM):
408.92
Formula:
C24H25ClN2O2
CAS No:
284035-33-2, 324523-20-8 (HCl)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 82 mg/mL
Solubility (25℃)
Water < 1mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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