Product name : GSK-2606414
Item : CR1798
Price : 200mg, $659;500mg, $1150; 1g, $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com
CAS : 1337531-36-8
Molecular Weight : 451.44
Formula : C₂₄H₂₀F₃N₅O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Chemical Information
Biological Activity of GSK2606414
GSK2606414 is an orally available, potent, and selective PERK inhibitor with an IC50 of 0.4 nM.
References on GSK2606414[1]. Axten JM, Medina JR, Feng Y, Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem. 2012 Aug 23;55(16):7193-207. |
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