Product name : AGI-6780
Item : CR1781
Price : 200mg, $659;500mg, $1150; 1g, $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com
CAS : 1432660-47-3
Molecular Weight : 481.51
Formula : C₂₁H₁₈F₃N₃O₃S₂
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order,Please ask price and availability of other quantities
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Chemical Information
Biological Activity of AGI-6780
AGI-6780 is the first highly potent and selective small molecule inhibitor of isocitrate dehydrogenases, which binds in an allosteric manner at the dimer interface of mutant IDH2-R140Q (IC50=23 nM).
Clinical Information of AGI-6780MORE
References on AGI-6780[1]. Wang F, et al. Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science. 2013 May 3;340(6132):622-6. |
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