Product name : IWR-1 (Synonyms: endo-IWR 1; IWR-1-endo)
Item : cc 714
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1127442-82-3
Molecular Weight : 409.44
Formula : C₂₅H₁₉N₃O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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IWR-1-endo is a potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response with an IC50 value of 180 nM. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. [1][2]
Reference:
[1] Nature Chem. Biol. 2008, 5, 100.
[2] Bioorg. Med. Chem. Lett. 2009, 19, 3825-3827.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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