Product name : PF-04449913
Item : CR1825
Price : 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
contact : Send inquiry to: info@acesobio.com
CAS : 1095173-27-5
Molecular Weight : 374.44
Formula : C₂₁H₂₂N₆O
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Chemical Information
Biological Activity of PF-04449913
PF-04449913 is a potent and orally bioavailable inhibitor of smoothened with IC50 of 5 nM(Gli-luciferase reporter reporter in C3H10T1/2); the hedgehog pathway inhibitor.
References on PF-04449913[1]. Michael J. Munchhof, et al. Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened. ACS Med. Chem. Lett., 2012, 3 (2), pp 106–111 |
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