Product name : MK 2048
Item : cc267
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 869901-69-9
Molecular Weight : 461.87
Formula : C₂₁H₂₁ClFN₅O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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MK-2048 is a second generation integrase inhibitor for integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively. MK2048 inhibits subtype B and subtype C integrase activities with IC50 of 75 nM and 80 nM, respectively.Integration of human immunodeficiency virus cDNA ends by integrase (IN) into host chromosomes involves a concerted integration mechanism. [1][2]
Reference:
[1] J Virol. 2012, 86, 2696-2705.
[2] Proc. Natl. Acad. Sci. USA 2010, 107, 20057-20062.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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