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Product name : Raltegravir (MK 0518)
Item : cc110
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 518048-05-0
Molecular Weight : 444.42
Formula : C₂₀H₂₁FN₆O₅
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectivly. Raltegravir (MK0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.  [1][2]
 
Reference:
[1] Proc. Natl. Acad. Sci. USA 2010, 107, 20057-20062.
[2] Mol. Pharmacol. 2011, 80, 565-572.
 
 
Chemical Information
Molecular Weight (WM):
444.42
Formula:
C20H21FN6O5
CAS No:
518048-05-0, 1292804-07-9 (sodium salt)
Purity:
≥ 98%
Synonyms:
Isentress, MK 0518
 
DMSO ≥ 50 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 2 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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