Favorite  |  Set Home
Products > Integrase/CCR5 > HIV Integrase > Raltegravir (MK 0518)
Product name : Raltegravir (MK 0518)
Item : cc110
Price : 100mg, $495; 200mg, $895;
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
             [Next Product]→


Details:
Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectivly. Raltegravir (MK0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.  [1][2]
 
Reference:
[1] Proc. Natl. Acad. Sci. USA 2010, 107, 20057-20062.
[2] Mol. Pharmacol. 2011, 80, 565-572.
 
 
Chemical Information
Molecular Weight (WM):
444.42
Formula:
C20H21FN6O5
CAS No:
518048-05-0, 1292804-07-9 (sodium salt)
Purity:
≥ 98%
Synonyms:
Isentress, MK 0518
 
DMSO ≥ 50 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 2 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
BMS 707035
BMS 707035
Price: 10mg, $265; 50mg, $795; 100mg, $1295; 200mg, $2295
Elvitegravir (GS-9137)
Elvitegravir (GS-9137)
Price: 10mg, $95; 50mg, $350; 100mg, $595; 200mg, $995
Dolutegravir (S/SGSK1349572)
Dolutegravir (S/SGSK1349572)
Price: 10mg, $265; 50mg, $795; 100mg, $1295; 200mg, $1995
MK 2048
MK 2048
Price: 10mg, $295; 50mg, $795; 100mg, $1295; 200mg, $1995