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Product name : Thiazovivin
Item : cc22
Price : 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1226056-71-8
Molecular Weight : 1226056-71-8
Formula : 311.36
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Thiazovivin is a selective, cell permeable small molecule that directly targets Rho-associated kinase (ROCK). In addition, Thiazovivin protects human embryonic stem cells (hESCs) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction1. This observation suggests that Thiazovivin promotes cell survival. In other studies Thiazovivin, in combination with inhibitors of the TGF-β receptor and MEK pathway, has shown to improve reprogramming efficiency by more than 200-fold.   [1][2]
 
Reference:
[1] Natl. Methods 2009, 6, 805-808.
[2] Cell Reprogram 2012, 14, 99-105.
 
 
Chemical Information
Molecular Weight (WM):
311.36
Formula:
C15H13N5OS
CAS No:
1226056-71-8, 1228446-06-7 (TFA)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 62 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 5 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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