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Product name : Linagliptin (BI 1356)
Item : cc405
Price : 10mg, $275; 50mg, $765; 100mg, $1295; 200mg, $2095
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Linagliptin (BI-1256) is an inhibitor of DPP-4, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Both GLP-1 and GIP increase insulin biosynthesis and secretion from pancreatic beta cells in the presence of normal and elevated blood glucose levels. GLP-1 also reduces glucagon secretion from pancreatic alpha cells, resulting in a reduction in hepatic glucose output. Thus, Linagliptin (BI1256) stimulates the release of insulin in a glucose-dependent manner and decreases the levels of glucagon in the circulation. [1][2]
 
Reference:
[1] Diabetes Obes. Metab. 2009, 11, 786-794.
[2] Curr. Med Res. Opin. 2009, 25, 1963-1972.
 
 
Chemical Information
Molecular Weight (WM):
472.54
Formula:
C25H28N8O2
CAS No:
668270-12-0
Purity:
≥ 98%
Synonyms:
Tradjenta, BI 1356
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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