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Product name : Epothilone A
Item : cc632
Price : 5mg, $375; 10mg, $595; 50mg, $2795;
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Epothilone A is a Taxol-like microtubule-stabilizing agent with EC0.01 of 2 μM. Epothilone A binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. The agent is not a substrate for the P-glycoprotein (P-gp) efflux pump and so may exhibit activity in multidrug-resistant (MDR) tumors. [1][2]
 
Reference:
[1] J Med. Chem. 1991, 34, 1176-1184.
[2] Org. Lett. 2011, 3, 2693-2696.
 
 
Chemical Information
Molecular Weight (WM):
493.66
Formula:
C26H39NO6S
CAS No:
152044-53-6, 1285540-20-6 (2H2O)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 99 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 99 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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