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Product name : Pifithrin-α
Item : cc 688
Price : 10mg, $125; 50mg, $395; 100mg, $695; 200mg, $995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. It enhances cell survival after genotoxic stress such as UV irradiation and treatment with cytotoxic compounds including doxorubicin, etopoxide, paclitaxel, and cytosine-β-D-arabinofuranoside. Pifithrin-α protects against neuronal death in models of stroke and neurodegenerative disorders.  [1][2]
 
Reference:
[1] Science 1999, 285, 1733-1737.
[2] Biochemistry 2000, 65, 41-48.
 
 
Chemical Information
Molecular Weight (WM):
369.32
Formula:
C16H18N2OS.HBr
CAS No:
63208-82-2, 206983-57-5 (free base)
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 67 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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