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Product name : VE 821
Item : cc 726
Price : 10mg, $125; 50mg, $395; 100mg, $595; 200mg, $895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively. Inhibition of the key DNA damage response kinase ATR has been suggested as an attractive approach for sensitization of tumor cells to DNA damaging agents.  [1][2]
 
Reference:
[1] Nat. Chem. Biol. 2011, 7, 428-430.
[2] J Med. Chem. 2011, 54, 2320-2330.
 
 
Chemical Information
Molecular Weight (WM):
368.41
Formula:
C18H16N4O3S
CAS No:
1232410-49-9
Purity:
≥ 98%
Synonyms:
VE821
 
DMSO ≥ 74 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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