Product name : CZC-25146
Item : CR1851
Price : 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
contact : Send inquiry to: info@acesobio.com
CAS : 1330003-04-7
Molecular Weight : 525.0
Formula : C₂₂H₂₆ClFN₆O₄S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Chemical Information
Biological Activity of CZC-25146 hydrochloride
CZC-25146 Hcl is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively.
References on CZC-25146 hydrochloride[1]. Ramsden N, et al. Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons. ACS Chem Biol. 2011 Oct 21;6(10):1021-8. |
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