Favorite  |  Set Home
Products > Protease > HCV Protease > Telaprevir (VX 950)
Product name : Telaprevir (VX 950)
Item : cc71
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 402957-28-2
Molecular Weight : 679.85
Formula : C₃₆H₅₃N₇O₆
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Telaprevir (VX-950) is a hepatitis C virus (HCV) NS3-4A serine protease inhibitor with IC50 of 0.35 μM. Telaprevir inhibits the hepatitis C virus NS3-4A serine protease, leading to the block of viral polyprotein processing and subsequently decrease of viral RNA replication. VX950 (17.5 μM) completely eradicates HCV RNA from replicon cells after 13 days incubation without rebound after Telaprevir is withdrawn. [1][2]
 
Reference:
[1] J Biol. Chem. 2004, 279, 17508-17514.
[2] J Biol. Chem. 2005, 280, 36784-36791.
 
 
Chemical Information
Molecular Weight (WM):
679.85
Formula:
C36H53N7O6
CAS No:
402957-28-2
Purity:
≥ 98%
Synonyms:
VX 950
 
DMSO ≥ 136 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

Related Products :
BMS 790052
BMS 790052
Price: 2g, $650;5g, $1050; 10g $1650
Danoprevir
Danoprevir
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
VX 222 (VCH 222)
VX 222 (VCH 222)
Price: 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
Boceprevir  (SCH-503034)
Boceprevir (SCH-503034)
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
PSI 6130
PSI 6130
Price: 100mg, $1290;200mg, $1895;
PSI 7977
PSI 7977
Price: 1g, $650;2g, $1050; 5g $1650
Elesclomol (SAT 4783)
Elesclomol (SAT 4783)
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355