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Product name : Danoprevir
Item : cc74
Price : 5mg, $195, 10mg, $295, 50mg, $895, 100mg, $1295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with an IC50 of 0.2-3.5 nM.Preclinical data demonstrated that danoprevir binds with high affinity and dissociates slowly from the HCV NS3 protease, allowing high liver drug exposure with only modest plasma drug exposure.  [1][2]
 
Reference:
[1] J Infect. Dis. 2008, 198, 800-807.
[2] Hepatolgy 2011, 53, 1090-1099.
 
 
Chemical Information
Molecular Weight (WM):
717.85
Formula:
C35H48FN5O8S
CAS No:
850876-88-9, 916881-67-9, 1001913-18-3, 1225266-12-5
Purity:
≥ 98%
Synonyms:
RG7227, ITMN-191, RO5190591
 
DMSO ≥ 144 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 144 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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