Favorite  |  Set Home
Products > Protease > HCV Protease > Danoprevir
Product name : Danoprevir
Item : cc74
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 850876-88-9
Molecular Weight : 731.83
Formula : C₃₅H₄₆FN₅O₉S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Danoprevir is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with an IC50 of 0.2-3.5 nM.Preclinical data demonstrated that danoprevir binds with high affinity and dissociates slowly from the HCV NS3 protease, allowing high liver drug exposure with only modest plasma drug exposure.  [1][2]
 
Reference:
[1] J Infect. Dis. 2008, 198, 800-807.
[2] Hepatolgy 2011, 53, 1090-1099.
 
 
Chemical Information
Molecular Weight (WM):
717.85
Formula:
C35H48FN5O8S
CAS No:
850876-88-9, 916881-67-9, 1001913-18-3, 1225266-12-5
Purity:
≥ 98%
Synonyms:
RG7227, ITMN-191, RO5190591
 
DMSO ≥ 144 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 144 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
Telaprevir (VX 950)
Telaprevir (VX 950)
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
VX 222 (VCH 222)
VX 222 (VCH 222)
Price: 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
PSI 7977
PSI 7977
Price: 1g, $650;2g, $1050; 5g $1650
BMS 790052
BMS 790052
Price: 2g, $650;5g, $1050; 10g $1650
Elesclomol (SAT 4783)
Elesclomol (SAT 4783)
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
Boceprevir  (SCH-503034)
Boceprevir (SCH-503034)
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
PSI 6130
PSI 6130
Price: 100mg, $1290;200mg, $1895;