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Product name : BMS 790052
Item : cc39
Price : 2g, $650;5g, $1050; 10g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1009119-65-6
Molecular Weight : 811.8
Formula : C₄₀H₅₂Cl₂N₈O₆
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
BMS-790052 is a first-in-class, highly selective inhibitor of hepatitis C virus (HCV) NS5A with an EC50 of 9–50 pM. NS5A is an essential component for hepatitis C virus (HCV) replication complex.Daclatasvir (BMS790052; EBP 883)has broad genotype coverage and exhibits picomolar in vitro potency against genotypes 1a (EC50 50pm) and 1b (EC50 9pm).Daclatasvir (BMS 790052; EBP 883) produces a robust decline in HCV RNA (-3.6 logs after 48 hours from a single 100 mg) dosefollowing a single dose in patients chronically infected with HCV genotype 1. [1][2]
 
Reference:
[1] Nature 2010, 465, 96-100.
[2] Virology 2011, 414, 10-18.
 
 
Chemical Information
Molecular Weight (WM):
738.88
Formula:
C40H50N8O6
CAS No:
1214735-16-6, 1009119-64-5
Purity:
≥ 98%
Synonyms:
BMS 790052
 
DMSO ≥ 148 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 148 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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