Product name : TAK 438
Item : cc 677
Price : 1g, $650;2g, $1050; 5g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1260141-27-2
Molecular Weight : 461.46
Formula : C₂₁H₂₀FN₃O₆S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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TAK-438 is a novel potassium-competitive acid blocker (P-CAB) type antisecretory agent that reversibly inhibits gastric H+,K+-ATPase with IC50 of 19 nM at pH 6.5. TAK438 exerts a more potent and longer-lasting inhibitory action on gastric acid secretion than either lansoprazole or SCH28080. TAK 438 is a novel antisecretory drug that may provide a new option for the patients with acid-related disease that is refractory to, or inadequately controlled by, treatment with PPIs. [1][2]
Reference:
[1] J Pharmacol. Ther. 2010, 335, 231-238.
[2] Biochem. Pharmacol. 2011, 81, 1145-1151.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE. |
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