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Product name : TAK 438
Item : cc 677
Price : 10mg, $295; 50mg, $895; 100mg, $1495; 200mg, $2195
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
TAK-438 is a novel potassium-competitive acid blocker (P-CAB) type antisecretory agent that reversibly inhibits gastric H+,K+-ATPase with IC50 of 19 nM at pH 6.5. TAK438 exerts a more potent and longer-lasting inhibitory action on gastric acid secretion than either lansoprazole or SCH28080. TAK 438 is a novel antisecretory drug that may provide a new option for the patients with acid-related disease that is refractory to, or inadequately controlled by, treatment with PPIs. [1][2]
 
Reference:
[1] J Pharmacol. Ther. 2010, 335, 231-238.
[2] Biochem. Pharmacol. 2011, 81, 1145-1151.
 
 
Chemical Information
Molecular Weight (WM):
461.46
Formula:
C17H16FN3O2S.C4H4O4
CAS No:
1260141-27-2, 881681-00-1 (free base)
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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